@article{amo15,
author = {Amor T. A., and Russo R., and Diez I., and Mudnal P., and Zirovich M., and Stramaglia S., and Cortes J. M., and DE ARCANGELIS Lucilla, and Chialvo D. R.,},
pages = {6},
title = {Extreme brain events: Higher order statistics of brain resting activity and its relation with structural connectivity},
volume = {111},
note = {Articolo in rivista},
issn = {0295-5075},
journal = {EUROPHYSICS LETTERS},
year = {2015},
abstract = {The brain exhibits a wide variety of spatiotemporal patterns of neuronal activity
recorded using functional magnetic resonance imaging as the so-called blood-oxygenated-level
dependent (BOLD) signal. An active area of work includes efforts to best describe the plethora of
these patterns evolving continuously in the brain. Here we explore the third-moment statistics of
the brain BOLD signals in the resting state as a proxy to capture extremeBOLD events. We find
that the brain signal exhibits typically nonzero skewness, with positive values for cortical regions
and negative values for subcortical regions. Furthermore, the combined analysis of structural and
functional connectivity demonstrates that relatively more connected regions exhibit activity with
high negative skewness. Overall, these results highlight the relevance of recent results emphasizing
that the spatiotemporal location of the relatively large-amplitude events in the BOLD time series
contains relevant information to reproduce a number of features of the brain dynamics during
resting state in health and disease.}
}